منابع مشابه
Balancing Acts Molecular Control of Mammalian Iron Metabolism
Iron is ubiquitous in the environment and in biology. The study of iron biology focuses on physiology and homeostasis-understanding how cells and organisms regulate their iron content, how diverse tissues orchestrate iron allocation, and how dysregulated iron homeostasis leads to common hematological, metabolic, and neurodegenerative diseases. This has provided novel insights into gene regulati...
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Hypoxia is a common feature in solid tumours. In glioma, it is considered the major driving force for tumour angiogenesis and correlates with enhanced resistance to conventional therapies, increased invasiveness and a poor prognosis for patients. Here we describe, for the first time, that miR675-5p, embedded in hypoxia-induced long non-coding RNA H19, plays a mandatory role in establishing a hy...
متن کاملGranulocyte Colony-Stimulating Factor Activating HIF-1α Acts Synergistically with Erythropoietin to Promote Tissue Plasticity
Stroke and peripheral limb ischemia are serious clinical problems with poor prognosis and limited treatment. The cytokines erythropoietin (EPO) and granulocyte-colony stimulating factor (G-CSF) have been used to induce endogenous cell repair and angiogenesis. Here, we demonstrated that the combination therapy of EPO and G-CSF exerted synergistic effects on cell survival and functional recovery ...
متن کاملProductivity Improvement through Line Balancing by Using Simulation Modeling
The typical problems facing garment manufacturers are long production lead time, bottlenecking, and low productivity. The most critical phase of garment manufacturing is the sewing phase, as it generally involves a number of operations or for the simple reason that it’s labor intensive. In assembly line balancing, allocation of jobs to machines is based on the objective of minimizing the workfl...
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ژورنال
عنوان ژورنال: Nature Immunology
سال: 2011
ISSN: 1529-2908,1529-2916
DOI: 10.1038/ni.2129